Luke P. Lee 教授 特別講演会

日時: 2005年09月21日(水) 09:00〜11:00
場所: 京都大学 工学部物理系校舎 3階 315講義室
講演者: Prof. Luke P. Lee (University of California, Berkeley)
講演題目: Nanophotonic Crescents with Cellular BASICs for Quantitative Systems Biology
講演要旨:

Nanophotonic crescents and Biologic Application Specific Inergrated Circuits (BASICs) are developed for quantitative systems biology and molecular preventive medicine. Biocompatible gold-based nanophotonic crescents have structures with a sub-10 nm sharp edge,which can enhance local electromagnetic field at the edge area. Metallic quantum plasmonic nanocrescents are ideal for nanoscale spectroscopic molecular imaging and photothermal therapeutic applicaitions. The formation of asymmetric nanophotonic crescent structure is accomplished for the precise control of surface enhanced Raman scattering (SERS) hot spot coupling nanogap.

Soft-state cellular BASICs are created by connecting existing and novel nano-or micro fluidic circuits for high speed biological and pharmaceutical analysis in new ways. We are creating a library of these “building blocks” to develop multifunctional biochip systems. In order to build a solid foundation of future quantitative biology and systematic bioinformatics for preventive medicine, we are currently establishing critical modules of BASICs such as Intergrated Multiple Patch-clamp Array Chip Technology (IMPACT), multiplexed cell culture chip array, sample preparation chip, cell lysing chip, cell separation, single cell electroporation chip, and cell-cell communication biochip for gap junction studies. The nanocrescent SERS probes and BASICs can be used for sensitive molecular detection, which has enormous benefits inearly disease detection, and drug discovery.


京都大学大学院 工学研究科 機械理工学専攻 マイクロエンジニアリング専攻 航空宇宙工学専攻
情報学研究科 複雑系科学専攻
京都大学 国際融合創造センター
拠点リーダー 土屋和雄(工学研究科・航空宇宙工学専攻)
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